Medscape 16 février 2018

L'exercice peut aider à prévenir la psychose chez des jeunes à haut-risque

Exercise may improve positive and negative symptoms, as well as social and cognitive function, in youth at ultra-high risk (UHR) for psychosis, new research shows.

Results from a pilot study in 12 UHR adolescents and young adults who participated in a supervised aerobic exercise regimen showed improvements in clinical, social, and cognitive domains as well as changes in brain function in regions affected by psychosis.

"The results of this study suggest that exercise interventions are feasible within UHR samples and may help to improve important domains that are affected during the development of psychosis," the researchers, with first author Derek J. Dean, University of Colorado at Boulder, write.

"Unique to this study from others in psychosis is the examination of brain structure and functional connectivity, suggesting that exercise may lead to change in the functional organization of the cortical-hippocampal networks," they add.
The study was published in the November/December issue of the Journal of Clinical Psychiatry.

A Supervised Exercise Intervention for Youth at Risk for Psychosis: An Open-Label Pilot Study. November 2017. The Journal of Clinical Psychiatry 78(9)